In 2005 she appeared in three acclaimed off-West End productions (Laura Wade's Colder Than Here, as well as The Philanthropist (directed by David Grindley) and The Cosmonaut's Last Message..., both at the Donmar Warehouse), and rounded off the year with a starring role in the National Theatre's adaptation of Jamilla Gavin's novel Coram Boy.

In 2007, Madeley appeared in Channel 4's Consent, which combined a dramatised vignette about an alleged date rape with a "real life" sequence in which lawyers and a jury made up of members of the public participated in a trial.

In February 2007, Madeley played Nina in a production of The Seagull for a time, when the main actress fell ill.

She then trained at the Central School of Speech and Drama.

She acted in The Roman Actor opposite Sir Antony Sher.

The film was shown on the opening night at the Frameline Film Festival at the Castro Theatre in San Francisco in June 2010.

In January 2013 Madeley starred in Hammer Films' first live theatre play, a new stage adaptation of The Turn of the Screw.She performed for three seasons with the Royal Shakespeare Company and she appeared in three off-West End productions. Anna has done work in radio, film, stage and television.Madeley grew up in London, attending North London Collegiate School, and began her career as a child actress.I haven’t had much experience working with children before but I think they are brilliant; real sponges for picking things up and incredibly fearless.I know what it is like to be in their shoes because I caught the acting bug very young.It happened by accident: I used to go to old-fashioned speech lessons once a week for confidence in reading and a bit of fun.